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黄连素对顽固性心力衰竭的疗效观察 被引量:11

Effects of Berberine on the Intractable Heart Failure
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摘要 目的:研究黄连素对顽固性心力衰竭的疗效。方法:选择2008年1月~2010年3月住院的顽固性心力衰竭病人32例,随机分成治疗组和对照组,均给予强心利尿、扩血管等常规抗心力衰竭治疗。治疗组病人除常规治疗外,给予黄连素5片,一日三次治疗,所有病人均在治疗前、治疗后两周用心脏彩色多普勒超声测量舒张期左室容积(EDV)、收缩末期左室容积(ESV)、每搏输出量(SV)、心输出量(CO)、射血分数(EF)、左心室舒张早期/晚期速度峰值比值(VE/VA)EA,比较两组心功能参数的差别。结果:治疗组与对照组相比,差异有显著意义(P<0.05)。结论:黄连素对顽固性心力衰竭治疗效果显著。 Objective:This thesis focused on the effects of herberine on the Intractable Heart Failure.Methods:32 inpatients suffered from Intractable Heart Failure who lived in the hospital from Jan.2008 to Mar.2010 were selected and randomly divided into therapy group and control group,while they were equally rcceived the regular treatment of anti-heart failure such as cardiac diuretic and vasodilatation,the therapy group were additionally treated by bcrberinc,3 times a day,5 tablets each time,All the inpatients were both tested twice by cardio color doppler ultrasound(CDU),one was 2 weeks before the therapy and the other was 2 weeks after the therapy.The testing items,which were included LVEDV, LVESV, SV, CO,EF,VE/VA,were designed to compare the differences between their respective left- ventricular-function.Results:Significance of difference between the said 2 groups were observed in this study (P〈0.05).Conclusion:Effects ofberberine on the intractable heart failure are significant.
作者 周宏 张旭
出处 《中国医药导刊》 2011年第7期1204-1205,共2页 Chinese Journal of Medicinal Guide
关键词 顽固性心力衰竭 黄连素 难治性心力衰竭 Berbcrine Intractable heart failure Refractory heart failure
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