摘要
目的:探讨新生儿缺氧缺血性脑病(HIE)血清中心肌酶谱的变化及临床意义。方法:对45例HIE患儿在治疗前后及40例正常新生儿的心肌酶谱谷草转氨酶(AST)、乳酸脱氢酶(LDH)、羟丁酸脱氢酶(HBDH)、肌酸激酶(CK)及同工酶(CK-MB)进行测定和分析。结果:HIE组与对照组间心肌酶谱比较差异均有统计学意义(P<0.01)且HIE患儿治疗前后心肌酶谱变化差异有统计学意义(P<0.01)。结论:心肌酶谱的测定对HIE判断病情轻重及治疗效果有重要的临床意义。
Objective：To observe the variation of myocardial enzyme in hypoxic ischemic encephatopathy （HIE） serum and clinical significancc.Methods：Myocardial enzymes aspartatc aminotransferase （AST）,lactate dehydrogenase （LDH）,hydroxybutyrate dehydrogenase （HBDH）,oreatine kinase （CK） and isoenzyme （CK-MB） Were measured and comprehensive analyzed for 45 infants With HIE before / after treatment and 40 healthy newborns.Results：There was significant statistical difference in myocardial enzymes between the HIE group and the control group （P〈0.01）,There was also significant statistical difference in myocardial enzyme variation before and after treatment in infants with HIE （P〈0.01）.Conclnsion：The measurement of myocardial enzyme has important clinical significance to assess the severity and treatment effects of HIE.
出处
《中国医药导刊》
2011年第7期1170-1171,共2页
Chinese Journal of Medicinal Guide
关键词
缺氧缺血性脑病
心肌酶谱
新生儿
Hypoxic ischemic encephalopathy
Myoeardial enzymes
Newborn
