摘要
基于蒙特卡罗(MC)方法的剂量计算算法已被普遍认为是可以在放射治疗中使用的最精确的计算工具。放射治疗中的MC模拟可分成两个部分,即对源的模拟和对实际患者的模拟。本文使用测量数据驱动的虚源模型建立了模拟直线加速器治疗头的虚拟源,通过与三维水箱中的测量数据比较,研究了虚拟源各种参数选择与计算精度之间的关系,表明考虑了初始光子源和次级光子源的综合影响,并选择合适的各种参数,由虚拟源出发的水模中的MC剂量分布可以与测量结果相一致,从而满足临床MC模拟的建模要求。
Dose calculation algorithms based on the Monte Carlo （MC） method are widely regarded as the most accurate tool available in radiotherapy. The MC simulation in radiotherapy has been split into two parts： the radiation source simulation and patient simulation. In this research, a virtual source for simulating the linear accelerator head was constructed with measurement-driven models. The dependence between the calculation accuracy and the specifi- cation of various parameters was studied by comparison between the measurement data and calculation results. It has been shown that the dose profile obtained by MC simulation can be consistent with measurement data, suggesting that the compound effect of primary photons and secondary photons are considered with appropriate parameter speci- fication. The requirement of modeling for MC simulation can be met in clinical conditions.
出处
《生物医学工程学杂志》
EI
CAS
CSCD
北大核心
2011年第5期932-935,945,共5页
Journal of Biomedical Engineering
关键词
蒙特卡罗模拟
虚拟源
测量数据驱动
参数选择
Monte Carlo （MC） simulation
Virtual source
Measurement-driven model
Parameter specification
