摘要
目的:探究大剂量阿司匹林联合低分子肝素在急性心肌梗死(AMI)治疗中的临床应用优势。方法:本文采用前瞻性研究,共收集83例AMI患者,随机分为研究组43例和对照组40例,分别用低分子肝素+阿司匹林治疗和普通肝素+阿司匹林治疗,再比较两组患者的情况。结果:将研究组治疗前后测得的PLT及FG进行t检验,t值分别为5.82及6.52,P值均<0.05;研究组和对照组的总有效率分别为95.3%和80.0%,进行卡方检验后,χ2=8.82,P<0.05,差异有统计学意义。结论:大剂量阿司匹林联合低分子肝素治疗AMI,可以有效地抗血栓,同时较小影响机体的抗凝作用,值得在临床上推广应用。
Objective：To explore the clinical advantage of high-dose aspirin combined with low molecular heparin in the treatment of acute myocardial infarction.Methods：With the prospective study,83 cases were collected,divided into study group 43 cases and control group 40 cases randomly,who were given high-dose aspirin combined with low molecular heparin and unfractionated heparin respectively.Then the differences between the two groups were compared.Results：According to the t-test,the PLT and FG measured before and after treatment,t values were 5.82 and 6.52 respectively,P〈0.05;The total effective rate of study group and control group were 95.3% and 80.0% respectively,according to the Chi-square test,χ2=8.82,P〈0.05.Conclusion：High-dose aspirin combined with low molecular heparin in the treatment of AMI,with effective antithrombotic and less anticoagulant effect,is worthy of clinical application.
出处
《中国当代医药》
2011年第28期55-56,共2页
China Modern Medicine
关键词
阿司匹林
大剂量
低分子
肝素
急性心肌梗死
Aspirin
High-dose
Low molecular
Heparin
Acute myocardial infarction
