摘要
目的检测二氧化氯的灭菌性能与毒理。方法采用杀菌试验对二氧化氯的杀菌效果进行实验观察;通过二氧化氯对小鼠骨髓细胞微核试验结果,检测其毒理作用。结果浓度为82 mg/L的二氧化氯稀释液,作用2.5 min5、.0 min、7.5 min,对金黄色葡萄球菌的平均杀灭对数值均>5.00,对大肠杆菌的平均杀灭对数值均>5.00;二氧化氯各剂量组、阴性对照组与阳性对照组比较,小鼠骨髓细胞微核率(‰)有极显著性差异(P<0.01),二氧化氯各试验组与阴性对照组比较无显著性差异(P>0.05)。结论受试的二氧化氯对大肠杆菌和金黄色葡萄球菌均具有优良的杀灭效果,对小鼠骨髓嗜多染红细胞无致微核作用。
Objective To detect chlorine dioxide sterilizing properties and toxicology.Methods Bactericidal test for chlorine dioxide sterilizing effect observation;by chlorine dioxide on mouse bone marrow cells micronucleus test resulted for the detection of the toxicological effect.Results The concentration of 82 mg/L chlorine dioxide dilution,the role of 2.5 min,5.0 min,7.5 min,against staphylococcus aureus average killing to numerical value was greater than 5.00,the average killing of Escherichia coli to numerical values were greater than 5.00;chlorine dioxide in each dosage group,negative control group and positive control group comparison,mouse bone marrow cell micronucleus rate（‰） had very significant difference（P0.01）,chlorine dioxide each test group compared with the negative control group,no significant difference（P0.05）.Conclusion The subjects of chlorine dioxide on escherichia coli and staphylococcus aureus should be excellent efficacy,on mouse bone marrow polychromatic erythrocyte micronucleus effect induced by.
出处
《黑龙江医学》
2011年第10期739-740,共2页
Heilongjiang Medical Journal
关键词
二氧化氯
灭菌
毒理
Chlorine dioxide
Sterilization
Toxicology
