摘要
目的:研究甘松根茎的化学成分。方法:运用大孔树脂Diaion HP-20、硅胶、反相ODS、Sephadex LH-20等柱色谱方法,结合制备型HPLC进行分离纯化,根据理化性质和MS、NMR等波谱学数据进行结构鉴定。结果:从甘松根茎中分离鉴定了6个化合物,分别为:8-羟基松脂醇-4-O-β-D-吡喃葡萄糖苷(1)、8-羟基松脂醇-4'-O-β-D-吡喃葡萄糖苷(2)、8-羟基松脂醇-4-O-(β-D-吡喃葡萄糖基)-4'-O-β-D-吡喃葡萄糖苷(3)、环橄榄脂素-6-O-β-D-吡喃葡萄糖苷(4)、阿魏酸(5)、绿原酸甲酯(6)。结论:化合物1～6均为首次从该属植物中分离得到。
Objective： To study the chemical constituents of roots and stems of Nardostachys chinensis.Methods： The chemical constituents were isolated and purified by column chromatography including silica gel,Diaion HP-20,Sephadex LH-20,ODS,and HPLC.Their structures were elucidated on the basis of spectral data analyses.Results： Six compounds were isolated and identified as 8-hydroxypinoresinol-4-O-β-D-glucopyranoside（1）,8-hydroxypinoresinol-4′-O-β-D-glucopyranoside（2）,8-hydroxypinoresinol-4-O-（β-D-glucopyranosyl）-4′-O-β-D-glucopyranoside（3）,cycloolivil 6-O-β-D-glucopyranoside（4）,ferulic acid（5）,chlorogenic acid methyl ester（6）.Conclusion： All the compounds are isolated from this genus for the first time.
出处
《中药材》
CAS
CSCD
北大核心
2011年第8期1216-1219,共4页
Journal of Chinese Medicinal Materials
关键词
甘松
根茎
化学成分
Nardostachys chinensis Batal.
Roots and stems
Chemical constituents
