摘要
为探讨联合检测血清β-人绒毛膜促性腺激素β-HCG和孕酮(P)在早期异位妊娠诊断及保守治疗中的价值,采用放射免疫分析法测定324例早期异位妊娠患者血清β-HCG和P水平,并与146名早期正常妊娠者作对照,比较保守治疗前后血清β-HCG和P水平的变化,观察治疗成功组患者血清β-HCG和P水平下降至正常范围内所需要的时间。结果显示,异位妊娠组血清β-HCG和P水平低于宫内妊娠组,差异有统计学意义(P<0.05);保守治疗成功组和失败组血清β-HCG下降幅度的差异无统计学意义(P>0.05),但P下降幅度的差异有统计学意义(P<0.05);保守治疗成功组和失败组对比,血清P比β-HCG更快下降至正常水平。因此,联合检测血清β-HCG和P可辅助确诊早期异位妊娠,为患者赢得治疗时机的同时对预后监测也具有临床意义。动态血清P测定可作为一种优于血清β-HCG的预测异位妊娠保守治疗效果的检测手段。
To explore the value of combined detection of serum β-HCG and P in diagnosis of early ectopic pregnancy and expectant therapeutic efficacy.Serum levels of β-HCG and P of 324 patients with early ectopic pregnancy and 146 normal early pregnant women were determined and compared by RIA,Serum β-HCG and P were compared between before and after treatment.The required time when serum β-HCG and P decreased to the normal rang of the patients treated successfully were observed respectively.The results showed that the serum β-HCG and P value in ectopic pregnancy group were significantly lower than those in intrauterine gestation group（P〈0.05）.The variation of P was significant between success and failure groups of drug conservative treatment,but β-HCG had no significant difference.The required time when serum P decreased to the normal was significantly less than the serum β-HCG dropped to normal.Combined detection of serum levels of β-HCG and P is an adjunctive method to diagnose early ectopic pregnancy,so it giants opportunity for treatment of early ectopic pregnancy and is of positive clinical application value for observation therapeutic effect and prognosis of the disease.P values may be one of the more important reference index to predict whether conservative treatment is successful or not than β-HCG.
出处
《标记免疫分析与临床》
CAS
2011年第5期305-308,共4页
Labeled Immunoassays and Clinical Medicine
