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宫颈癌调强放射治疗研究新进展 被引量:12

Recent Research Progress in Intensity Modulated Radiation Therapy for Patients of Cervical Cancer
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摘要 放射治疗作为宫颈癌主要治疗方法之一,外照射逐渐用调强适形放疗(IMRT)代替四野箱式照射技术和盆腔前后对穿照射技术,而影像引导放疗开创了精确放疗到精准放疗的时代。内照射开始采用以二维影像为基础的治疗计划代替三维影像为基础的近距离放疗技术,为宫颈癌的放射治疗能更有效地减轻正常组织并发症,提高疗效打下更坚实的基础。目前,IMRT在妇科恶性肿瘤中应用时间相对较短且病例数较少,其安全性及有效性有待于进一步证实。但IMRT与三维高剂量率近距离放疗结合仍是放疗界关注的焦点。 Radiotherapy is one of the most common treatments for cervical cancer.Intensity modulated radiation therapy(IMRT)has gradually replaced four fields radiation technique or two fields A-P radiation therapy in EBRT,and the image-guide radiotherapy(IGRT)starts a new era in exact radiotherapy.Brachytherapy based on 2-D image has gradually been replaced by 3-D image.It is possible to further reduce the normal tissue complications probability and improve tumor control probability in radiotherapy of uterine cervix cancer.At present,IMRT application in gynecologic malignancy has not been long and case number is small.The safety and efficacy of IMRT for cervical cancer need to be further confirmed.However,the combination of IMRT and 3-D HDR brachytherapy is still the focus of radiotherapy in cervical cancer.
出处 《医学综述》 2011年第20期3077-3080,共4页 Medical Recapitulate
基金 卫生部吴阶平基金项目(WKJ2005-3-006-18)
关键词 宫颈癌 调强放射治疗 三维近距离放疗 影像引导放疗 Cervical cancer Zntensity radiation therapy 3D-brachytherapy IGRT
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