2Akarca US , Greene S,Log ASF. Detection of precore hepatitis B virus mutants in a symptomatic HBsAg-positive family members. Hepatology, 1994,19(6):1336
3骆抗先.乙型肝炎基础和临床（第2版）[M].北京:人民卫生出版社,2001.415-435.
4Lai CL, Chien RN, Leung NW, et al. A one-year trial to lamivudine for chronic hepatitis B. N Engl J Med, 1998,339:61-68.
5Leung NWY, Lai CL, Chang TT. Three year lamivudine therapy HBV. J Hepatol, 1999,30:59.
6Pichoud C, Berby F, Stuyver L, et al. Persistence of viral replication after anti-HBe seroconversion druing antiviral therapy for chronic hepatitis B. J Hepatol, 2000,32:307-316.
7Dienstag JL, Schiff ER, Mitchell M, et al. Extended lamivudine retreatment for chronic hepatitis B: maintenance of viral suppression after discontinuation of therapy. Hepatology, 1999,30:1082-1087.
8Lok AS, McMahon BJ. Chronic Hepatitis B. Hepatology, 2001,34:1225-1241.
9Bartholomew MM, Jansen RW, Jeffers LJ, et al. Hepatitis B virus resistance to lamivudine given for recurrent infection after orthotopic liver transplantation. Lancet, 1997,349:20-22.
10Thibault V, Benhamou Y, Seguret C, et al. Hepatitis B virus(HBV) mutations associated with resistance to lamivudine in patients coinfected with HBV and human immunodeficiency virus. J Clin Microb, 1999,8:3013-3016.
