摘要
目的:探讨妊娠合并血小板减少围产期的处理及母儿预后。方法:回顾性分析妊娠合并血小板减少38例孕妇及新生儿的临床资料。结果:妊娠合并特发性血小板减少性紫殿(ITP)10例,发生率26.3%;妊娠合并血小板减少症24例,发生率63.2%;妊高征合并血小板减少4例,发生率10.5%;伴有妊娠期肝内胆汁淤积症4例;产后出血3例。阴道分娩8例,其中产妇颅内出血1例;剖宫产分娩30例。无孕产妇死亡,无新生儿血小板减少、无颅内出血发生。进行孕期治疗,血小板>50×109/L,无需特殊处理,血小板<50×109/L需要糖皮质激素和免疫球蛋白治疗,术前、术中予血小板悬液输注。结论:妊娠合并血小板减少根据不同病因及病情轻重的程度而采取不同的处理方式,处理及时,母婴均较安全。糖皮质激素、免疫球蛋白及血小板悬液是治疗血小板减少的有效方法。
Objective：To investigate the impact of pregnancy associated thrombocytopenia on the outcomes of pregnancy.Methods：Medical records of 38 pregnant women with thrombocytopenia and their neonatal outcomes were reviewed retrospectively from January 2008 to November 2010 in our hospital.Results：The incidence of pregnancy with ITP was 26.3%;with thrombocytopenia was 63.2%;pregnancy induced hypertension 10.5%.The maternal complications included intrahepatic cholestasis of pregnancy（ICP） 4 cases;postpartum hemorrhage 3 cases.There were 8 cases delivered by vagina and 30 cases delivered by cesarean section;Among them one mother had an intracranial hemorrhage;No maternal mortality was noted;No neonatal thrombocytopenia and intracranial hemorrhage.Conclusion：Appropriate treatment shall be applied according to the specific pathogenesis,causes and clinical response of pregnancy with thrombocytopenia,The prognosis of mothers and neonates in pregnancy with thrombocytopenia are better.Glucocorticoids,gamma globulin and transfusion of platelets are effective methods for the treatment of thrombocytopenia in pregnancy.
出处
《陕西医学杂志》
CAS
2011年第10期1300-1302,共3页
Shaanxi Medical Journal
关键词
妊娠
血小板减少
新生儿
预后
Pregnancy Thrombocytopenia Neonatal Outcome
