摘要
目的分析近年来浙江台州市甲状腺癌的临床流行病学新特点,探讨其发病趋势及防治措施。方法对台州市立医院2004-2009年手术治疗的320例甲状腺癌临床资料分类,按性别、年龄、病理类型等进行描述性分析,用SPSS 12.0软件进行χ2检验。结果男女性别比为1∶2.4。发病年龄<40岁患者,2004-2006年共21例(18.3%),2007-2009年共69例(33.7%),两者比较差异有统计学意义(P<0.01)。200例术前B超提示甲状腺癌,术后确诊166例,诊断符合率占83.0%。甲状腺乳头状癌303例(94.7%)。96例伴发甲状腺良性疾病(30.0%),其中合并桥本甲状腺炎44例(13.8%)。微小癌167例(52.2%),前后3年间所占比率分别为44.3%和57.6%,差异有统计学意义(P<0.05)。结论台州地区甲状腺癌发病女性高于男性。发病年龄呈提前趋势,病理类型仍以乳头状癌为主,甲状腺癌合并良性结节以桥本甲状腺炎为主,微小癌检出率明显增高,B超发现甲状腺癌起关键作用。对此应有针对性地采取综合性的防治措施。
Objective To make a clear vision of trend in thyroid cancer incidence and corresponding preventative modalities by analyzing clinical epidemological features of thyroid cancer in Taizhou. Methods 320 cases of thyroid cancer with surgical treatment from 2004 to 2009 in Taizhou Municipal Hospital were reviewed.All cases were separated into subgroups by gender,age and pathological diagnosis for descriptive analysis.Pearson Chi-square by SPSS 12.0 software was used for statistical analysis. Results The ratio of thyroid cancer in female to male was 1∶2.4.For the group of age ≤40,an increase in cumulative cases from 2007 to 2009(69 cases,33.7% of all cases) with statistical significance was observed compared with that in years from 2004 to 2006(21 cases,18.3% of all cases).166 cases of thyroid cancer were diagnosed by subsequent surgery out of 200 cases which were diagnosed by ultrosonigraphy beforehand,with an corresponding diagnosis rate of 83.0%.A total of 303(94.7%) cases of thyroid papillary carcinoma were found.Ninety-six cases of thyroid cancer were accompanied with benign lesions,including Hashimoto′s thyroiditis in 44(13.8%).Thyroid microcarcinom was found in 167 cases,accounting for 52.2% of all paillary carcinoma,and the proportion of thyroid microcarcinoma was raised from 44.3% in 2004-2006 to 57.6% in 2007-2009(P0.05). Conclusions Thyroid cancer in Taizhou tends to happen more in females and in earlier age.Papillary carcinoma is the main category of thyroid cancer.Hashimoto's thyroiditis is the most common concomitant disease in thyroid carcinoma,number of thyroid microcarcinoma cases is increased remarkably.B Ultrasonic examination plays a key role in the diagnosis of thyroid carcinoma.It is necessary to take comprehensive measures for prevention and treatment of thyroid cancer.
出处
《实用肿瘤杂志》
CAS
北大核心
2011年第5期514-516,共3页
Journal of Practical Oncology