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儿童上呼吸道感染中C反应蛋白和外周血白细胞的变化 被引量:18

The study of the changes of C-reactive protein and peripheral blood leucocyte in pediatric patients suffering from upper respiratory infection
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摘要 目的探讨C反应蛋白(CRP)和外周血白细胞在小儿上呼吸道感染中作用。方法对102例上呼吸道感染患儿和20例健康儿童血液中CRP和外周血白细胞水平进行检测。结果细菌感染组CRP和外周血白细胞水平均高于健康对照组(P<0.05),病毒感染组与健康对照组差异均无统计学意义(P>0.05);67例上呼吸道细菌感染患儿中CRP阳性者为43例,占64.2%,而外周血白细胞阳性者31例,占46.3%,差异有统计学意义(P<0.05)。上呼吸道感染患儿血中CRP和外周血白细胞水平呈正相关(r=0.346,P<0.01)。结论上呼吸道感染患儿血中CRP和外周血白细胞水平可用来区分细菌性及病毒性感染,二者在感染过程中有协同作用,联合检测可为临床合理用药提供指导。 Objective To study the effect of C-reactive protein(CRP)and peripheral blood leucocyte in pediatric patients suffering from upper respiratory infection.Methods CRP and peripheral blood leucocyte was detected respectively in 102 cases of pediatric patients suffering from upper respiratory infection and 20 cases of normal children.Results The results showed that the contents of CRP and peripheral blood leucocyte in bacterial infection group were significantly higher than those in the normal group(P〈0.05),and showed no significant difference between viral the infection group and the normal group(P〈0.05).Among the 67 cases of pediatric patients suffering from upper respiratory infection,43 cases were CRP positive and 31 cases were peripheral blood leucocyte positive,and the difference was significant(P〈0.05).CRP level was correlated with the peripheral blood leucocyte(r=0.346,P〈0.01).Conclusion The detection of CRP and peripheral blood leucocyte can be used to distinguish bacterial infection from viral infection.They may coordinate with each other in the procession of infection and may be used to guide clinical proper drug usage.
出处 《检验医学与临床》 CAS 2011年第20期2466-2467,共2页 Laboratory Medicine and Clinic
关键词 C反应蛋白 外周血白细胞 上呼吸道感染 C-reactive protein peripheral blood leucocyte upper respiratory infection
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