摘要
文章介绍了合成5-氨基邻甲苯酚工艺路线,并改进了以邻甲苯胺为合成基本原料进行合成大红色基G、重氮化、水解,最后还原的制备工艺,在原料选择、工艺参数设计、能耗方面做出了重大改进,并且取得了很大的效果,主要选择邻甲苯胺作原料,利用正交法优化了反应条件,得到了合适的反应时间、反应温度和投料比及较理想的产率。通过分析比较,该工艺在国内比较先进,具有原料易得、工艺稳定、收率高、技术合理可靠、目标产物纯度高等优点。
The papaer introduced the synthesis of 5-amino o-methylphenol process route,and improved the synthesis process with o-toluidine as the basic raw material for the synthesis of large red base G,diazotization,hydrolysis,preparation of the final reduction in raw material selection,process parameter design,energy consumption.In the it made significant improvements and achieved great results,the main choice of o-toluidine as raw material,the use of orthogonal reaction conditions were optimized to obtain the appropriate reaction time,reaction temperature and the molar ratio and more good yield.Through analysis and comparison,the more advanced technology in the country,with material accessible,process stability,high yield,reasonable and reliable technology,the higher purity in target product and so on.
出处
《广东化工》
CAS
2011年第10期24-25,共2页
Guangdong Chemical Industry
基金
湖北省教育厅资助项目(Q20102605)
襄樊学院大学生科研项目(2010DXS204)
关键词
5-氨基邻甲苯酚
重氮化
水解
正交设计
5-amino o-methylphenol
diazotization
hydrolysis
orthogonal design
