摘要
目的观测并探讨膝骨关节炎关节液及血清中聚蛋白多糖酶(ADAMTSs)水平与病变程度的关系。方法单侧膝骨关节炎87例中,早期为45例,中晚期为42例。检测其患侧膝关节液和血清中ADAMTSs水平。以健康志愿者30例为正常对照组。结果膝骨关节炎患者关节液及血清中AD-AMTSs水平均高于正常对照组,随着病变程度加重,膝关节液及血清中ADAMTSs水平显著增加,关节液与血清中ADAMTSs水平存在线性相关关系。结论 ADAMTSs水平在骨关节炎患者膝关节液和血清中均升高,与病变程度密切相关,检测关节液及血液该种指标有助于病情早期诊断。
Objective To observe and discuss the relationship between levels of ADAMTSs in synovial fluid and knee osteoarthritis in serum and the degree of pathological change. Methods Among 87 patients with single-side knee osteoarthritis, 45 of them suffered from early-stage knee osteoarthritis, and 42 of them from medium-later-stage knee osteoarthritis. Examined levels of ADAMTSs in synovial fluid and serum. The control group was 30 healthy volunteers. Results Levels of ADAMTSs in synovial fluid and serum in these patients＇ bodies were higher than those of the control group. As the degree of pathological change becomes increasingly serious, such levels were increased significantly, and there was linear relationship between levels of ADAMTSs in synovial fluid and those in serum. Conclusion Levels of ADAMTSs in synovial fluid and serum in bodies of persons suffering from knee osteoarthritis are increased, and there is close relationship between the degrees of pathological change. Examination of levels of ADAMTSs in synovial fluid and serum facilitates diagnosis at early stage.
出处
《中国实用医药》
2011年第24期13-14,共2页
China Practical Medicine
基金
昆明医学院联合基金项目(项目编号:2008CD048)
