摘要
肝性脑病作为肝脏疾病终末期常见的并发症之一,严重降低病人的生活质量,影响疾病预后。不合理的营养摄入是肝性脑病的诱因之一。支链氨基酸的应用不仅可预防肝病病人发生肝性脑病,还可以降低肝性脑病病人的意识障碍。本文简述肝性脑病的发生机制,并从理论基础、临床研究叙述支链氨基酸的治疗作用机制,且对常见支链氨基酸药物及已报道的不良反应进行综述,目的在于规范支链氨基酸在肝性脑病中的应用,提高医师对其不良反应的重视。
As one of the common complications in the liver disease end-stage,hepatic encephalopathy seriously lowers the quality of patient lives and affects disease prognosis.Unreasonable nutritional intake is one of the reasons that lead to hepatic encephalopathy.The use of branched chain amino acids not only can prevent patients from hepatic encephalopathy,but also can lower the disorder of consciousness.This paper briefly narrates the happening mechanism of hepatic encephalopathy and lists the common medicine containing branched chain amino acids.Besides,it summarizes the adverse reactions reported,aiming to set standards to the use of branched chain amino acids.
出处
《氨基酸和生物资源》
CAS
2011年第3期63-66,共4页
Amino Acids & Biotic Resources
关键词
支链氨基酸
肝性脑病
branched chain amino acids
hepatic encephalopathy
