摘要
目的:探讨P-选择素和血小板参数的检测在肺炎患者的病情评估及预后判断中的临床意义。方法:选取2008年1月～2010年12月在我院住院的急性肺炎患者126例,将其分为重症肺炎组(42例)和轻症肺炎组(84例),同时,随机选取100例健康体检者作为对照组,比较三组患者的P-选择素和血小板参数检查结果。结果:急性肺炎患者的血小板(PLT)明显增高,与健康体检者比较,差异有高度统计学意义(P<0.01);重症肺炎组的P-选择素、PLT明显增高,血小板分布宽度(PDW)、平均血小板容积(MPV)及大血小板比例(P-LCR)明显降低,与轻症肺炎组和对照组比较,差异均有高度统计学意义(均P<0.01);轻症肺炎组的P-选择素、PDW、MPV及P-LCR与对照组比较,差异均无统计学意义(P>0.05)。结论:血小板参数及功能状态异常是肺炎患者普遍存在的病理过程,检测肺炎患者的P-选择素、血小板参数可作为评估疾病进程及预后的一项参考指标。
Objective： To investigate the clinical significance of detection of P-selectin and platelet parameters in the illness evaluation and therapeutic effect of patients with pneumonia.Methods： 126 cases of patients with acute pneumonia in our hospital from January 2008 to December 2010 were divided into severe pneumonia group（42 cases） and mild pneumonia group（84 cases）,at the same time,100 cases of healthy persons were chosen as control group.The test results of P-selectin and platelet parameters between the three groups were compared.Results： PLT of patients with acute pneumonia was higher than that of control group with significant difference（P〈0.01）;P-selectin and PLT of severe pneumonia group increased significantly,while PDW,MPV and P-LCR decreased,compared with mild pneumonia group and control group,there were significant differences（P〈0.01）;P-selectin,PDW,MPV and P-LCR of mild pneumonia group had no significant difference compared with control group（P〉0.05）.Conclusion： Abnormal results of platelet parameters and functional status of patients with pneumonia is a common pathological process.The test results of P-selectin,platelet parameters in patients with pneumonia can be used as an important index to valuate the progress of the disease and an index for estimation of the prognosis.
出处
《中国医药导报》
CAS
2011年第27期77-78,共2页
China Medical Herald
关键词
肺炎
P-选择素
血小板参数
Pneumonia
P-selectin, Platelet parameters
