摘要
目的探讨赖诺普利、曲美他嗪对急性冠脉综合征合并2型糖尿病患者血管内皮功能及糖化血红蛋白的影响，及心脏事件发生情况。方法治疗组采用赖诺普利、曲美他嗪治疗，对照组采用传统方法治疗；在改善血管内皮功能、降低糖化血红蛋白、防治心血管事件等方面比较疗效。结果治疗组在改善血管内皮功能、降低糖化血红蛋白（7．0％VS．8．0％）、防治心血管事件（13例vs．23例）等方面优于对照组。结论赖诺普利、曲美他嗪对急性冠脉综合征合并2型糖尿病患者，可显著改善血管内皮功能、降低糖化血红蛋白、防治心血管事件，患者多方面受益。
Objective To explore effects of lisinopril and trimetazidine treating acute coro- nary artery syndrome combined with 2-type diabetes mellitus, such as blood vessel endothelium function and glycosylated hemoglobin effect and heart blood vessel event of acute coronary artery syndrome combined with 2-type diabetes mellitus. Methods Therapy group offered lisinopril and trimetazidine, control group received traditional method, compared with curative effect of improving blood vessel endothelium function, depressing glycosylated hemoglobin, preventing and curing heart blood vessel event. Results Therapy group is better than control group in improving blood vessel endothelium function, depressing glycosylated hemoglobin, preventing and curing heart blood vessel event. Conclusion Lisinopril and trimetazidine can improve blood vessel endothelium function, depress glycosylated hemoglobin, prevent and cure heart blood vessel event of acute coronary artery syndrome combined wih 2-type diabetes mellitus. Patients can benefit from it in many ways.
出处
《国际医药卫生导报》
2011年第18期2214-2217,共4页
International Medicine and Health Guidance News
基金
云浮市科技计划（医药卫生）项目（2009W一16）
关键词
赖诺普利
曲美他嗪
血管内皮功能
糖化血红蛋白
心脏事件
Lisinopril
Trimetazidine
Blood vessel endothelium function
Glycosylatedhemoglobin
Heart event
