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SLP-2的研究进展

Progress on SLP-2 study
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摘要 SLP-2(Stomatin like protein-2)是Stomatin基因超家族的一员,其蛋白分子定位及功能目前还没有被完全的了解。近年来的研究发现,SLP-2蛋白分子可能定位于细胞线粒体中,并且与多种肿瘤的发生发展及预后存在一定的联系。本文将对SLP-2的研究进展进行论述。
作者 王跃锜 郭文杰 牛蓓 郭晓恒 曹丽丽
机构地区 成都大学医护学院
出处 《四川生理科学杂志》 2011年第3期126-128,共3页 Sichuan Journal of Physiological Sciences
关键词 SLP-2 线粒体 肿瘤
分类号 R730.2 [医药卫生—肿瘤]
  • 相关文献

参考文献25

  • 1Wang Y, Morrow JS. Identification and characterization of human SLP-2, a novel homologue of stomatin (band 7. 2b) present in e- rythrocytes and other tissues[J]. J Biol Chem, 2000, 275 (11): 8062-8071.
  • 2Goldstein BJ, Kulaga NM, Reed RR. Cloning and characterization of SLP-3: a novel member of the stomatin family expressed by olfac- tory receptor neurons[J]. J Assoe Otolaryngol, 2003, 4 (1) : 74- 82.
  • 3Owczarek CM, Trentlein HR, Portbury KJ, et al. A novel member of the STOMATIN/EPB72/mec-2 family, stomatin-like 2 (STOML2), is ubiquitously expressed and localizes to HSA chro- mosome 9p13. 1[J]. Cytogenet Cell Genet, 2001, 92(3--4):196-- 203.
  • 4Liu J, Deyoung SM, Zhang M, et al. The stomatin/prohibitin/flo- tillin/HflK/C domain of flotillin-1 contains distinct sequences that direct plasma membrane localization and protein interactions in 3T3- 1.1 adipoeytes[J]. J Biol Chem, 2005, 280(16):16125-16134.
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  • 7Haglund K, Ivankovie-Dikic I, Shimokawa N, et al. Recruitment of Pyk2 and Cbl to lipid rafts mediates signals important for aetin reor- ganization in growing neurites[J]. J Cell Sci, 2004, 117(Pt 12): 2557-2568.
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二级参考文献22

  • 1张逊.食管癌TNM分期的现状及发展趋势[J].中华肿瘤杂志,2004,26(11):641-644. 被引量：24
  • 2张立勇,丁芳,刘仲敏,李文东,刘芝华,李衍达.SLP-2基因反义核酸对食管鳞癌细胞系TE12生长和增殖的影响[J].癌症,2005,24(2):155-159. 被引量：24
  • 3Luo A,Kong J,Hu G,et al.Discovery of Ca^2+-relevant and differentiation-associated genes downregulated in esophageal squamous cell carcinoma using cDNA microarray.Oncogene,2004,23:1291-1299.
  • 4Zhi H,Zhang J,Hu G,et al.The deregulation of arachidonic acid metabolism-related genes in human esophageal squamous cell carcinoma.Int J Cancer,2003,106:327-333.
  • 5Wang Y,Morrow JS.Identification and characterization of human SLP-2,a novel homologue of stomatin (band 7.2b) present in erytuocytes and other tissues.J Biol Chem,2000,275:8062-8071.
  • 6Owczarek CM,Treutlein HR,Portbury KJ,et al.A novel member of the STOMATIN/EPB72/mec-2 family,stomatin-like 2 (STOML2),is ubiquitously expressed and localizes to HSA cuomosome 9p13.1.Cytogenet Cell Genet,2001,92:196-203.
  • 7Sprenger RR,Speijer D,Back JW,et al.Comparative proteomics of human endothelial cell caveolae and rafts using two-dimensional gel electrophoresis and mass spectrometry.Electrophoresis,2004,25:156-172.
  • 8Zhang L,Ding F,Cao W,et al.Stomatin-like proteinn 2is overexpressed in cancer and involved in regulating cell growth and cell adhesion in human esophageal squamous cell carcinoma.Clin Cancer Res,2006,12:1639-1646.
  • 9Cui Z,ZhangL,Hua Z,et al.Stomatin-like protein 2 is overexpressed and related to cell growth in human endometrial adenocarcinoma.Oncol Rep,2007,17:829-833.
  • 10Cao WF,Zhang LY,Liu MB,et al.Prognostic significance of stomatin-like protein 2 overexpression in laryngeal squamous cell carcinoma:clinical,histological and immunohistochemistry analysis with tissue microarray.Hum Pathol,2007,38:747-752.

共引文献33

四川生理科学杂志
2011年 第3期

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