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EHF患者血清特异性IgG的动态观察及其与病情的关系

SERIAL DETERMINATION OF SPECIFIC SERUM ANTIBODY IgG IN PATIENT WITH EHF AND RELATIONSHIP TO SEVERITY OF DISEASE
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摘要 采用ELISA间接法对流行性出血热病程中及病后180天血清特异性IgG抗体的消长情况进行了系统的动态观察,并按病情轻重进行了对比分折。特异性抗体IgG在病后1~5天即出现,第20天下降,病后180天仍维持在一定水平。重型患者抗体水平高于轻、中型患者(P<0.01)。提示这种特异性抗体反应可能与病情的严重程度有关。 Specific serum antibody IgG in 34 patients with epidemic hemorrhagic five (EHF) from the onset of the disease to 180 days after healing was determined serially by indirect enzyme linked immunosorbent assay and analysed comparatively according to the severity of the eisease.The antibody IgG appeared on the first of fifth day, reached its peak at the fourteenth day, declined at the twentyth day, and kept a given level at 180 days after the onset of the disease.The level of antibody in severe patients is higher than that of the moderate and minor patients (P<0.001).It is suggested that the specific antibody reaction may be related to the severity of the disease.
出处 《新乡医学院学报》 CAS 1990年第1期40-42,共3页 Journal of Xinxiang Medical University
关键词 流行性出血热 特异IgG抗体 epidemic hemorrhagic fever indirect enzyme linked immunosorbent assay specific antibody IgG
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