摘要
目的研究苦黄注射液联合腺苷蛋氨酸注射液治疗高胆红素血症的疗效。方法将2009年12月至2011年3月本院收治的40例高胆红素血症患者按随机原则均分为两组。对照组以腺苷蛋氨酸注射液1．0g静脉滴注（静滴）；治疗组在对照组基础上加用苦黄注射液30ml静滴，两组均每日1次，3周为1个疗程。观察两组治疗后血清总胆红素（TBil）、碱性磷酸酶（ALP）、γ-谷氨酰转肽酶（γ-GT）的变化。结果治疗组显效率明显高于对照组（80％比50OA，P〈O．05）。两组治疗后肝功能均较治疗前明显好转，血清TBil（umol／L：对照组65．14±22．23比137．76±54．66，治疗组37．89±16．69比145．60±58．72）、ALP（U／L：对照组143．11±66．34比211．23±10．57，治疗组：142．31±41．58比221．35±65．96）、γ-GT（U／L：对照组116．45±92．69比187．82±124．41，治疗组108．30±83．44比198．13±17．26）均较治疗前明显下降（P〈0．05或P〈0．01），且以治疗组TBil下降更显著（umol／L：37．89±16．69比65．14±22．23，P〈0．05）。结论苦黄注射液联合腺苷蛋氨酸注射液治疗高胆红素血症的疗效较好。
Objective To study the clinical efficacy of Kuhuang injection （苦黄注射液） combined with Ademetionine injection for treatment of hyperbilirubinemia. Methods From December 2009 to March 2011 in our unit, 40 cases of hyperbilirubinemia were randomly divided into two groups equally. The control group was treated by intravenous drip of Ademetionine injection 1.0 g, once a day. Besides the treatment in the control group, the treatment group additionally received Kuhuang injection 30 ml intravenous drip once a day. The therapeutic course of treatment for both groups was 3 weeks. Serum level of total bilirubin （TBil）, alkaline phosphatase （ALP） and γ-glutamyl transpeptidase （γ-GT） were detected to compare the therapeutic effects in the two groups. Results The efficiency in treatment group was higher than that in the control group （80% vs. 50%, P〈0. 05）. After treatment, the liver function in both groups improved obviously compared to that before the treatment. The serum level of TBil （umol/L： the control group 65.14±22.23 vs. 137.76±54.66; the treatment group 37.89±16.69 vs. 145.60±58. 72）, ALP （U/L： the control group 143. 11±66.34 vs. 211.23±110. 57; the treatment group 142.31±41.58 vs 221.35±65.96） and γ-GT （U/L： the control group 116.45 ± 92.69 vs. 187.82 ± 124. 41; the treatment group 108.30± 83.44 vs. 198.13 ± 117.26） were significantly decreased after treatment in both groups （P〈0. 05 or P〈0.01）. The serum level of TBil in treatment group declined more significantly than that in control group （umol/L： 37.89±16.69 vs. 65.14± 22.23,P〈 0. 05）. Conclusion The therapeutic effect of Kuhuang injection combined with Ademetionine injection for treatment of hyperbilirubinemia is better than that applying ademetionine injection alone.
出处
《中国中西医结合急救杂志》
CAS
北大核心
2011年第4期201-202,共2页
Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care
基金
国家中医药管理局中医药重点学科（中医肝胆病学）建设项目
江苏省中医药管理局资助项目（LZ09029）
关键词
苦黄注射液
腺苷蛋氨酸注射液
高胆红素血症
中西医结合疗法
Kuhuang injection
Ademetionine injection Hyperbilirubinemia
Combination of traditional Chinese and western medicine treatment
