全麻及硬膜外麻醉对骨科大手术老年患者术后早期认知功能的影响被引量：78

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摘要目的观察全麻及硬膜外麻醉对老年骨科大手术患者术后早期认知功能的影响。方法选择180例择期行骨科大手术(如人工髋关节置换术、人工膝关节置换术、髋部周围骨折手术)的老年(≥65岁)患者,按所用的麻醉方法分为全身麻醉组(全麻组)和硬膜外麻醉组(硬膜外组),各90例。两组均于术前1 d及术后第1、4天采用简易精神状态检查(MMSE)量表行认知功能检测。术后MMSE得分较术前得分降低≥2分者即为发生了术后认知功能障碍(POCD)。结果全麻组中有72例、硬膜外组中有80例完成认知功能检测。术后第1天全麻组POCD发生率为34.7%(25/72),硬膜外组为22.5%(18/80);术后第4天分别为19.4%(14/72)、15.0%(12/80);两组比较,P均>0.05。结论在全身麻醉和硬膜外麻醉下,骨科大手术老年患者术后早期均可发生POCD,这两种麻醉导致POCD率相似。

作者刘沁爽李淮安梁淑娟孙海军

机构地区秦皇岛市第一医院

出处《山东医药》 CAS 北大核心 2011年第26期68-69,共2页 Shandong Medical Journal

基金河北省科技研究与计划项目(10276136)

关键词全身麻醉硬膜外麻醉外科手术认知障碍老年

分类号 R614.2 [医药卫生—麻醉学] R614.3 [医药卫生—麻醉学]

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