摘要
目的:观察间苯三酚在分娩第一产程潜伏期和活跃期应用对产程和母婴安全的影响。方法:选择我院待产分娩的足月单胎头位、宫颈痉挛水肿的初产妇80例,随机分成观察组和对照组各40例。观察组分别在潜伏期和活跃期,对照组在活跃期给予间苯三酚80mg静脉注射。观察并比较2组产程进展时间、宫口扩张平均速度、产后出血和新生儿Apgar评分。结果:观察组潜伏期(4.03±0.40)h,活跃期(5.14±0.76)h,宫口扩张平均速度(2.71±1.52)cm/h;对照组分别为(5.26±0.51)h、(7.16±0.87)h和(1.82±1.02)cm/h,2组间差异均有统计学意义(均P<0.01)。观察组产后出血(210.16±14.07)mL,新生儿评分(9.90±0.35)分;对照组产后出血(204.37±13.23)mL,新生儿评分(9.77±0.33)分,2组间差异无统计学意义(均P>0.05)。结论:潜伏期和活跃期应用间苯三酚对于加速宫颈扩张、缩短产程优于只活跃期应用该药,并且对产妇和新生儿无不良影响。
Objective：To observe the effects of phloroglucinol on acceleration of labor and its side effects on puerpera and fetus.Methods：A randomized controlled trial was conducted on 80 uncomplicated full term,single birth and head position labors with cervix spasm or edema in Nankai Hospital,with 40 in study group and 40 in control group.The phloroglucinol was given to patients of study group at the dose of 80 mg intravenously in parturient phase and active phase respectively.And phloroglucinol was given to patients of the control group at the dose of 80 mg intravenously in active phase only.The duration of labor,average dilation speed of cervix,postpartum hemorrhage and neonatus Apgar score were observed respectively.Results：It was found that the parturient phase was（4.03±0.40）h,the active phase was（5.14±0.76）h,and the average accelerate rate of cervix dilation was（2.71±1.52）cm/h in study group compared with those of（5.26±0.51）h,（7.16±0.87）h and（1.82±1.02）cm/h respectively in control group.The differences were significant（P 0.01）.There were differences in postpartum hemorrhage（210.16±14.07）mL and neonatus Apgar score（9.90±0.35） in study group than those of（204.37±13.23）mL and（9.77±0.33） in control group.The differences were no statistical significance（P 0.05）.Conclusion：The effect of phloroglucinol given in parturient phase and active phase is superior to that of active phase only,with regard to acceleration of cervix dilation and reduction of the duration of labor,and with no side effects on puerperant and fetus.
出处
《天津医药》
CAS
北大核心
2011年第9期806-808,共3页
Tianjin Medical Journal
关键词
间苯三酚
分娩过程
产程
第一
产程
第二
分娩
产后出血
婴儿
新生
子宫颈
phloroglucinol labor
obstetric labor stage
first labor stage
second parturition postpartum hemorrhage infant
newborn cervix uteri
