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微淋巴管密度对直肠癌根治术后局部复发的预测作用

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摘要 目的探讨微淋巴管密度(LMVD)对直肠癌根治性术后局部复发的预测作用。方法回顾性分析2003年1月至2006年1月实施根治手术的352例直肠癌根治患者的临床资料.应用免疫组织化学法检测肿瘤组织LMVD。结果352例患者中术后局部复发34例.其LMVD(32.6±4.0)高于无局部复发组(26.8±3.6)(P=0.004)。多因素分析显示,LMVD、淋巴结转移、浸润深度和淋巴管侵犯为影响局部复发的独立因素.其中LMVD影响最大(OR=8.63.95%CI:3.01~17.44.P〈0.01)。结论LMVD可能预测直肠癌术后局部复发。
出处 《中华胃肠外科杂志》 CAS 北大核心 2011年第8期644-645,共2页 Chinese Journal of Gastrointestinal Surgery
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