摘要
老年性白内障 79例 ,随机分成两组 ,行超声乳化摘除联合人工晶体植入术。对照组灌注液为平衡盐液 ,实验组中灌注液为平衡盐液中加入肝素 5 0 IU/ ml,观察对后囊混浊的影响。结果术后 1年纤维化型后囊混浊明显减少 ,说明肝素在一定程度上抑制后囊混浊的发生。作用机制可能是抗炎、抑制晶体上皮细胞生长和溶解纤维蛋白等。肝素组 2例前房少量积血 ,常规治疗 3天内吸收 ,角膜反应与对照组相同 。
patients with senile cataract were randomly assigned to two groups for phacoemulsification.Infusion solutions was BSS in the control group and BSS plus heparin(50Iu/ml)in the drug group.The result showed that the fibrotic posterior capsular opacification(PCO)decreased significantly one year after the operation,indicating heparin being effective in inhibiting PCO.The possible mechanism is the efficacy of heparin in inhibiting the growth of len epithelium,anti inflammatory and dissolving fibrin.There was hyphema in two cases of the drug group,and the comeal reaction was similar to that of the control group.So the application of heparin was safe.
出处
《中国实用眼科杂志》
CSCD
1999年第12期747-748,共2页
Chinese Journal of Practical Ophthalmology
