摘要
目的： 探讨手术后置管后装照射治疗原发性肝癌的治疗效果。方法：自１９９８ 年１ 月至１９９８年１０ 月，将４０ 例行肝癌切除术的原发性肝癌患者随机分为放疗组和对照组，每组２０ 例。放疗组术中放置施源管（２～５ 根，平均３．８５ 根／人）；确定驻留点２～８ 个，平均３．７ 个／人；术后３～１４ ｄ 行后装放射治疗；单次照射剂量５～１０ Ｇｙ，平均８ Ｇｙ；照射共６８ 次，平均３．４ 次／人；总剂量１０～４０ Ｇｙ，平均３０ Ｇｙ。对照组术后不放疗。结果：放疗组治疗后，ＡＦＰ转阴率１００％ （１７／１７），高于对照组的７１％ （１０／１４）（Ｐ＜ ０．０５）；６ 个月复发率为０，低于对照组的２５％ （５／２０）（Ｐ＜ ０．０５）；６ 个月的生存率为１００％ （２０／２０），与对照组的９５％ （１９／２０）无显著差异（Ｐ＞ ０．０５）。结论：手术后置管后装照射是提高原发性肝癌近期治疗效果，降低复发率的有效手段。
Objective:To evaluate the effect of postoperative afterloading radiotherapy on 20 patients with primary liver cancer. Methods: From Jan. 1998 to Oct. 1998, 20 patients with primary liver cancer underwent postoperative after loading radiotherapy 3~14 days after hepatectomy, compared with 20 cases of sole hepatectomy. 2~5 ductus were placed for irradiation after hepatectomy, 3.85 ductus per person. The single dose was 5~10 Gy, averaging 8 Gy. Sixty eight sessions of irradiation were performed, 3.4 sessions per person. The total dose was 10~40 Gy, averaging 30 Gy. Results: The rate of AFP negative reversion was 100%(17/17) in treated group, higher than that in control group(10/14) ( P <0.05). The relapse rate within 6 months was 0(0/20) in treated group, lower than that in control group 25%(5/20) ( P <0.05). There was no significant difference between the 2 groups in 6 months survival rate. Conclusion: Postoperative afterloading radiotherapy is an effective way for the treatment of primary liver cancer.
出处
《第二军医大学学报》
CAS
CSCD
北大核心
1999年第11期901-903,共3页
Academic Journal of Second Military Medical University
