摘要
目的观察氟比洛芬酯在腹腔镜胆囊切除术应用时机。方法 ASAⅠ～Ⅱ级LC病人120例,随机分A、B、C三组,分别在手术开始后即刻、预计手术结束前30分钟及预计手术结束前10分钟静脉缓慢注射氟比洛芬酯50mg,麻醉诱导及维持均相同,手术结束后观察呼吸恢复、拔管时间、苏醒期躁动评分及离室前疼痛视觉模拟评分(VAS评分)。结果三组病人呼吸恢复、拔管时间比较均无统计学差异,离室前VAS评分B组为最低,A组和C组比较无统计学差异;三组病人苏醒期躁动发生率B组最低,A组和C组比较无统计学差异。结论氟比洛芬酯应用于腹腔镜下胆囊切除术有较确切的效果,手术结束前30分钟是最佳应用时机。
Objective To investigate the suitable time for flurbiprofen application in patients undergoing laparoscopic cholecystecomy.Methods 120 patients（ASA I or II） were randomly divided into three groups.Following the same induction and maintaining of general anesthesia,the group A patients were received 50 mg flurbiprofen at the initial of the surgery,and the group B patients were received 50 mg Flurbiprofen 30 min before the end of the surgery,the group C patients were received 50 mg flurbiprofen at the end of the surgery.Evaluation was taken for the time of restoration spontaneous ventilation and extubation,emergence agitation scores and VAS scores at postanesthesia care unit discharge.Results There were no statistically significant between the three groups in time of restoration spontaneous ventilation and extubation.Emergence agitation scores and VAS scores in group B were significantly lower than those in group A and group C,while there had no statistically significant between group A and group C.Conclusion Flurbiprofen exhibited the effective effect in patients with laparoscopic cholecystecomy,30 min before the end of the surgery might be the suitable dose time for flurbiprofen therapy.
出处
《临床医学工程》
2011年第8期1200-1201,共2页
Clinical Medicine & Engineering
关键词
氟比洛芬酯
腹腔镜
胆囊切除
镇痛
应用时机
Flurbiprofen
Laparoscopic
Cholecystecomy
Analgesia
Suitable time
