摘要
目的为探讨慢性肝病患者乙型肝炎病毒(HBV)、丙型肝炎病毒(HCV)、丁型肝炎病毒(HDV)感染情况及其相互间的关系。方法采用酶联免疫吸附法对236例慢性肝病患者进行HBV、抗-HCV、抗-HDV的检测。并对慢性肝炎、重症肝炎、肝硬化、肝癌的感染率作一分析。结果单纯HBV的感染率为61.8%,远大于单纯HCV(8.5%)和HDV(0.4%)感染率。单纯HDV感染率很低,HBV和HDV重叠感染率较高为(12.3%),并且HBV和HDV重叠感染率按慢性肝炎、重症肝炎、肝硬化、肝癌呈顺序递增现象。肝癌组的HBV、HCV重叠感染率12.5%,与慢性肝炎组(4.9%)差异有统计学意义。结论 慢性肝病患者仍以感染HBV为主,HBV易与HCV、HDV发生重叠感染。重叠感染易使肝病加重。支持HDV要在感染HBV的基础上感染。
Objective To explore the infection status of patients with chronic liver disease,including HBV,HCV,HDV infection and their relationships.Methods We used ELISA to test the HBV,anti-HCV,anti-HDV of 236 cases of chronic liver disease patients.And analyzed the infection rates of chronic hepatitis,severe hepatitis and liver cirrhosis,liver cancer.Results The infection rate of HBV was 61.8%,which was higher than the infection rates of HCV(8.5%) and HDV(0.4%).The HDV infection rate was very low,but the overlapping infection rate of HBV and HDV was high(12.3%),and the overlapping infection rate of HBV and HDV in chronic hepatitis infection,severe hepatitis and liver cirrhosis,liver cancer were in ascending order.The overlapping infection rate of HBV and HDV in liver cancer group was 12.5%,combined with that of chronic hepatitis group(4.9%),there was a significant difference.Conclusion The main infection of patients with chronic liver disease is the HBV,which often happen with the overlapping infection of HCV and HDV,that would make liver disease aggravated.
出处
《检验医学与临床》
CAS
2011年第15期1843-1844,共2页
Laboratory Medicine and Clinic
