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右美托咪定辅助颈丛阻滞甲状腺手术的临床研究 被引量:8

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摘要 目的观察右美托咪定辅助颈丛阻滞甲状腺手术的麻醉效果及对血流动力学的影响。方法 40例颈丛神经阻滞甲状腺手术病人随机分为2组,D组右美托咪定组(20例),C组0.9%氯化钠对照组(20例)。观察麻醉效果并记录颈丛阻滞前(T0)、切皮(T1)、分离腺瘤(T2)、手术结束(T3)等各时点的SBP、DBP、HR。结果 D组麻醉效果优于C组(P<0.05)。D组各时点SBP、DBP、HR较平稳。C组T1、T2、T3各时点SBP、DBP、HR较T0明显升高(P<0.05),D组T1、T2、T3各时点SBP、DBP、HR较C组明显下降(P<0.05)。结论右美托咪定辅助颈丛阻滞甲状腺手术,其镇静、镇痛作用好,血流动力学稳定。
作者 余小丽
出处 《江西医药》 CAS 2011年第6期558-559,共2页 Jiangxi Medical Journal
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参考文献5

  • 1李民,张利萍,吴新民.右美托咪啶在临床麻醉中应用的研究进展[J].中国临床药理学杂志,2007,23(6):466-470. 被引量:484
  • 2Pentti J, Helminen A,Anttila M,et al.Cardiovascular and parasympathetic effects of dexmetomidine in heahhysubjects.Canadian J Physiology and Pharmacology, 2004,82:359.
  • 3CarolloDS,Nossaman BD,RamadhyaniU.Dexmedetomidine: a review of clinical applications. Curt Opin Anesthesiol, 2008, 21(4): 457.
  • 4Bekper A,Sturaitis M,Bloom M,et al.The effect of dexmedetomodine on perioperative hemodynamics in patient undergoing craniotomy.Anesth Analg,2008,107(4):1340.
  • 5Ebert TJ,HALL JE ,Barney JA ,et al.The effcey of increasing plasm concentration of dexmedetomidine in humans.Anesthesiology,2000, 93:38.

二级参考文献39

  • 1[1]Khan ZP,Ferguson CN,Jones RM.Alpha-2 and imidazoline receptor agonists:their pharmacology and therapeutic role[J].Anesthesia,1999;54:146-165.
  • 2[2]Kamibayashi T,Maze M.Clinical uses of alpha 2-adrenergic agonists[J].Anesthesiology,2000;93:1345-1350.
  • 3[3]Calzada BC,De Artinano AA.[alpha]2-Adrenoreceptor subtypes[J].Pharmacol Res,2001;44:195-208.
  • 4[4]Hunter JC,Fontanna DJ,Hedley LR,et al.Assessment of the role of alpha 2-adrenoceptor subtypes in the antinociceptive,sedative and hypothermic action of dexmedetomidine in transgenic mice[J].Br J Pharmacol,1997;122:1339-1344.
  • 5[5]Nelson LE,Lu J,Guo TZ,et al.The α2-Adrenoceptor agonist dexmedetomidine converges on an endogenous sleep-promoting pathway to exert its sedative effects[J].Anesthesiology,2003;98:428-436.
  • 6[6]Coull JT,Jones M,Egan T,et al.Attentionla effects of noradranaline vary with arousal level:selective activation of thalamie pulvinar in humans[J].Neuro Image,2004;22:315-322.
  • 7[7]Eisenach JC.[Alpha]2 agonists and analgesia[J].Exp Opin Invest Drugs,1994;3:1005-1010.
  • 8[8]Ma D,Rajakumamswamy N,Maze M.Alpha2-Adrenoceptor agonists:shedding light on neuroprotection?[J].Br Med Bull,2005;71:77-92.
  • 9[9]Ebert TJ,Hall JE,Barney JA,et al.The effects of increasing plasma concentrations of dexmedetomidine in humans[J].Anesthesiology,2000;93:382-394.
  • 10[10]Ramsey MA,Luterman DL.Dexmedetomidine as a total intravenous anesthestic agent[J].Anesthesiology,2004;101:787-781.

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