摘要
目的研究99mTc-MIBI核素显像对临床疑似甲状腺癌的诊断价值。方法 99mTc-MIBI及99mTcO4-显像平行检测106例临床疑似甲状腺癌的甲状腺结节患者,与同期甲状腺彩超和临床病理诊断等进行对照研究。结果 99mTcO4-对甲状腺癌诊断灵敏度为82%,特异度为25%,诊断准确度为72%。99mTc-MIBI诊断灵敏度为81%,而特异度上升为75%,诊断准确度达到80%。当99mTcO4-诊断甲状腺癌患者为阴性结果时,99mTc-MIBI对其诊断为阳性的概率却达到了68.18%。结论99mTc-MIBI显像对甲状腺癌具有一定的定性诊断价值,其可显著提高99mTcO-阴性甲状腺癌患者的检出率。
Objective To investigate the diagnostic value of ^99mTc-MIBI thyroid scintigraphy for suspected thyroid cancer. Methods 106 consecutive patients with the suspected diagnosis of thyroid cancer were scanned by ^99mTc-MIBI and ^99mTcO4^- preoperatively. The results of ultrasound and pathology were analyzed at the same time. Results ^99mTcO4^- thyroid scintigraphy had a sensitivity of 82% and specificity of 25% as a diagnostic test for thyroid cancer. 99mTc-MIBI thyroid scintigraphy had a sensitivity of 81% and specificity of 75%. ^99mTc-MIBI thyroid seintigraphy had higher specificity, and its sensitivity was equal to that of 99mTeO4 . Furthermore,68% thyroid cancer patients with negative ^99mTeO4 could be detected as ^99mTc-MIBI positive. Conclusion These results indicate that ^99mTe-MIBI thyroid scintigraphy,as defined in our study, is a useful method in the assessment of thyroid cancer with a good potential for clinical application.
出处
《中南医学科学杂志》
CAS
2011年第3期302-304,共3页
Medical Science Journal of Central South China
