摘要
实验采用雄性SD大鼠心脏缺血再灌注模型，观察缺血预处理心肌组织MDA含量、SOD和CAT酶活性的变化。结果表明：缺血预处理组大鼠心肌SOD、CAT活性显著上升（P＜0．05），MDA含量显著减少（P＜0．01）。以上结果提示：缺血预处理对大鼠心脏的保护作用之一可能是通过提高SOD、CAT酶活性，减少脂质过氧化反应而实现的。
Changes of MDA contents and SOD, CAT activities in ischemic/reperfused rat myocardium with ischemicpreconditioning were investigated. The findings showed that SOD, CAT activities with ischemic preconditioningwent up significantly(P<0. 05)and MAD contents were obviously reduced(P<0.01). It is conc1uded that oneof the protective effects of ischemic preconditioning on the myocardium of the rat was brought about by raisedSoD, CAT activities and reduced MDA contents.
基金
湖北省自然科学基金!95J31
关键词
心肌缺血
MDA
SOD
CAT酶
缺血预处理
myocardial reperfusion injury
superoxide dismutase
catalase
animals, laboratory
rats
