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孟鲁斯特辅助治疗小儿咳嗽变异性哮喘64例疗效观察 被引量:12

Therapeutic efficacy of montelukast on children cough variant asthma
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摘要 目的:观察孟鲁斯特辅助治疗儿童咳嗽变异性哮喘的临床效果。方法:采用随机分组,对128例咳嗽变异性哮喘患儿按照1:1的比例随机分为治疗组和对照组,其中对照组64例,予舒喘宁、酮替芬口服及普米克雾化吸入。治疗组64例,在对照组治疗的基础上,加用孟鲁斯特口服。分析治疗后两组咳嗽症状的改善情况。结果:治疗组疗效明显好于对照组,两组有统计学意义(P<0.05)。结论:孟鲁斯特辅助治疗儿童咳嗽变异性哮喘疗效好,副作用少,值得推广。 Objective:To assess the efficacy of montelukast on cough variant asthma(CVA) .Methods:128 children with CVA in clinic from Jun 2010 to Dec 2010 were randomly divided into two groups in the ratio of 1:1:objective group(n=64) and control group(n=64) .All the children of two groups took ketotifen and salbutamol and inhaled Pulmicort(Budesonide) ,while those of objective group additionally took montelukast;The remission of cough was recorded. Results:The effective rate of objective group was higher than that of the control group;A significant difference existed between the two groups(P 0.05) .Conclusion:The montelukast is effective for CVA,and has a little by-effect. It is worthy of being widely used.
作者 邹嵘 邓少洁
出处 《北方药学》 2011年第5期17-18,共2页 Journal of North Pharmacy
关键词 孟鲁斯特 咳嗽变异性哮喘 小儿 Montelukast Cough variant asthma(CVA) Children
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