摘要
目的：探讨 Ｃ Ｄ４４ ｖ６ 在胃癌组织中的积聚与淋巴转移的关系。方法：采用免疫组织化学 Ｓ－ Ｐ法对４１ 例胃癌标本进行 Ｃ Ｄ４４ ｖ６ 的检测。结果：胃癌组织、转移淋巴结、癌旁组织 Ｃ Ｄ４４ ｖ６ 分别为 ５３．６６％ ，５４．８４ ％ ，２．４４％ ；前两者均明显高于后者（ Ｐ＜ ０．００５， Ｐ＜ ０．００５）；淋巴转移组 Ｃ Ｄ４４ ｖ６ 阳性率明显高于未转移组（ Ｐ＜ ０．０１）。结论： Ｃ Ｄ４４ ｖ６ 在胃癌组织中的积聚与淋巴转移明显相关。 Ｃ Ｄ４４ ｖ６ 的检测对胃癌淋巴转移的判断具有较高的价值。
Objective:To explore the relationships between CD44 v6 accumulation and lymphatic metastasis in gastric cancer.Methods:CD44v6 proteins were examined immunohistochemically in 41 cases of gastric cancer.Results:The respective accumulations of CD44v6 protein in gastric tumor, lymphatic metastasis tissue, and adjacent tissue of the tumor were 53.66%,54.84%,and 2.44%, the first two items being obviously higher(P<0.005,P<0.005). The positive rate was strikingly higher in lymphatic metastasis group than in the non-metastasis group (P<0.01).Conclusion:The accumulation of CD44v6 in gastric cancer was clearly related to the lymphatic metastasis. And ,therefore, CD44 v6 test is of great value to the judgment of the metastasis.
出处
《郧阳医学院学报》
1999年第3期127-128,共2页
Journal of Yunyang Medical College
