摘要
为临床治疗急性呼吸窘迫综合征(ARDS)寻找新的有效药物,选用蝮蛇抗栓酶(Svate)对ARDS动物模型进行防治,观察疗效。结果发现,Svate可使ARDS动物的各项病变有不同程度地减轻。实验表明,改善肺内微循环高凝状态是防治ARDS的一条重要途径,Svate有可能成为临床治疗ARDS的有效药物。
To find new drugs which have good therapeutic effect on acute lung injury (even to acute respiratory distress syndrome,ARDS),svate was selected to treat the ARDS in rat models. The results showed that svate could attenuate all injury of lungs in ARDS. The results suggested that improving pulmonary hypercoagulation state would be an effective method for ARDS,and svate might be an effective drug in clinical treatment.
