摘要
目的探讨糖尿病与胰腺癌的相关性,为胰腺癌的早期诊断提供依据。方法检索1990年1月至2011年2月Medline、Pubmed、中国学术期刊全文数据库、万方全文数据库公开发表的糖尿病与胰腺癌的病例对照研究文献,共收集到31篇文献。采用Review Manager 5.1软件对资料进行分析,结果纳入Meta分析的文献共8篇,病例对照研究总人数为6481例(名),累计胰腺癌患者2158例。经Meta分析,与未患胰腺癌者相比,胰腺癌患者糖尿病发病的OR值为5.51(95%CI值:4.67,6.50),差异有统计学意义(P<0.00001)。结论糖尿病可能是胰腺癌发病的危险因素,两者具有相关性。
Objective To investigate the association between diabetes and pancreatic cancer,provides the basis for the early diagnosis of pancreatic cancer.Methods We searched in Medline,Chinese CNKI and Wanfang databases from January 1990 to February 2011 to evaluate the relationship between diabetes and pancreatic cancer from case control study,a total of 31 publications were found.Results A total of 2158 cases of pancreatic cancer and 6481 study subjects from 8 literatures were included in our analysis.The odds ratio of diabetes was 5.51（95% CI： 4.67,6.50）for persons with pancreatic cancer when compared to subjects without pancreatic cancer.Difference was statistically significant（P0.00001）.Conclusion Diabetes may be risk factors for pancreatic cancer,the two are relevant.
出处
《实用医院临床杂志》
2011年第4期82-83,共2页
Practical Journal of Clinical Medicine
关键词
糖尿病
胰腺癌
META分析
相关性
Diabetes mellitus
Pancreatic cancer
Case-control study
Meta-analysis
