地特胰岛素减少体重增加的中枢机制探讨
Central nervous system mechanism of insulin detemir for less weight gain
摘要
2005年，全球约14亿成人处于超重状态，其中至少4亿属于肥胖人群；预计到2015年．上述数据可分别增加到23亿和7亿。如同全球的趋势一样．中国的肥胖患病率正在增加。
出处
《药品评价》
CAS
2011年第7期12-14,共3页
Drug Evaluation
参考文献15
-
1Lau DC. Diabetes and weight management[J]. Prim Care Diabetes, 2010, 4 Suppl 1:S24-S30.
-
2Wu Y. Overweight and obesity in China[J]. Br Med J, 2006, 333: 362-363.
-
3Morton GJ, Cummings DE, Baskin DG, et al. Central nervous system control of food intake and body weight[J]. Nature, 2006, 443(7109): 289-295.
-
4Woods SC, Seeley RJ, Baskin DG, et al. Insulin and the blood-brain barrier[J]. Curr Pharm Des, 2003, 9(10): 795-800.
-
5Woods SC, Lotter EC, McKay LD, et al. Chronic intracerebroventricular infusion of insulin reduces food intake and body weight of baboons[J]. Nature, 1979, 282(5738): 503-505.
-
6McGowan MK, Andrews KM, Kelly J, et al. Effects of chronic intrahypothalamic infusion of insulin on food intake and diurnal meal patterning in the rat[J]. Behav Neurosci, 1990, 104(2): 373-385.
-
7Benedict C, Kern W, Schultes B, et al. Differential sensitivity of men and women to anorexigenic and memory-improving effects of intranasal insulin[J].J Clin Endocrinol Metab, 2008, 93(4): 1339-1344.
-
8UK Prospective Diabetes Study (UKPDS) Group. Effect of intensive blood- glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34)[J].Lancet, 1998, 352: 854-865.
-
9Hallschmid M, Schultes B. Central nervous insulin resistance: a promising target in the treatment of metabolic and cognitive disorders[J]? Diabetologia, 2009, 52(11): 2264-2269.
-
10Fajardo MC, Hernandez HC, Rivas FM. Less weight gain and hypogiycaemia with once-daily insulin detemir than NPH insulin in intensification of insulin therapy in overweight type 2 diabetes patients: the PREDICTIVE BMI clinical trial[J].Diabet MeG 2008, 25: 916-923.
-
1胡雪,陈月,邹大进.肥胖、糖尿病与肿瘤:病理生理机制新进展[J].中华糖尿病杂志,2010,2(5). 被引量：4
-
2邹大进.2型糖尿病患者的血糖和体重——两者可以兼顾吗[J].中国糖尿病杂志,2009,17(11):877-878. 被引量：3
-
3李亚德.据美国一项调查显示：都市女性32％为超重状态[J].健康问答,2005(12):9-9.
-
4董玉梅,梁丽,刘国良.肥胖糖尿病及临床处理策略[J].实用糖尿病杂志,2012,8(3):4-6. 被引量：11
-
5贾晓清,蔡兰平,唐丽君,孔曲,张晓霞,李金梅,宋克群.对1513名离退休干部超重和肥胖情况的调查与分析[J].解放军护理杂志,2005,22(7):24-25. 被引量：9
-
6宦鹏年,王勇.某石化工业人群肥胖及相关危险因素的调查分析[J].中国慢性病预防与控制,2001,9(4):157-159. 被引量：2
-
7元小冬,徐建辉,张楠楠,王淑娟,李静.FgBβ基因多态性与其功能表达和肥胖的相关性研究[J].国际免疫学杂志,2012,35(5):384-389.
-
8Yu-Cheng Lin,Shu-Tin Hsiao,Jong-Dar Chen.Sonographic fatty liver and hepatitis B virus carrier status: Synergistic effect on liver damage in Taiwan Residents adults[J].World Journal of Gastroenterology,2007,13(12):1805-1810. 被引量：10
