摘要
目的：探讨新生儿缺氧缺血性脑病（hypoxnic-ischemic encephalopathy,HIE）的相关因素及临床特点。方法：回顾性分析2000年1月~2009年12月住院治疗的389例新生儿HIE发生因素及临床特点。结果：新生儿HIE的发生主要为宫内窘迫占74.3%,重度窒息引起新生儿HIE的发病率和死亡率均高于轻度窒息患儿。64.5%的患儿血生化异常,32.6%的患儿早期临床表现由兴奋逐渐转为抑制。结论：新生儿HIE的发生主要为宫内窘迫,特别是重度窒息,故对有宫内窘迫表现者,应及时终止妊娠。尽早治疗可避免脑组织进一步损害,减少并发症及后遗症,降低死亡率。
Objective：To study the clinical features and relevant factors in neonatal hypoxic ischemic encephalopathy（NHIC）.Methods：To perform the retrospective analysis on the occurrence factors and clinical features in 389 hospitalized cases of neonatal hypoxic ischemic encephalopathy from January 2000 to December 2009.Results：Among the causes of neonatal hypoxic ischemic encephalopathy,intrauterine asphyxia mainly accounted for 74.3%.The morbidity and mortality of hypoxic ischemic encephalopathy caused by severe neonatal asphyxia were higher than those of mild asphyxia.64.5% of neonatal patients had blood biochemical abnormalities.32.6% of neonatal patients revealed early clinical manifestations of excitement turning into suppression gradually.Conclusion：The main factor of neonatal hypoxic ischemic encephalopathy is intrauterine asphyxia,especially severe asphyxia.Pregnant women with the manifestation of intrauterine distress should terminate pregnancy in time.Treatment as early as possible can prevent further damage to brain tissues,reduce complications and sequelae and decrease mortality.
出处
《现代医药卫生》
2011年第14期2090-2091,共2页
Journal of Modern Medicine & Health
