摘要
目的分析甲型H1N1流感肺炎病例的临床特点。方法回顾性分析30例甲型H1N1流感肺炎患者的临床资料。结果患者男女比例相当,年龄17～54岁,23.3%有慢性疾病史,26.7%为孕产妇,病死率为13.4%。重症与轻症患者比较,其呼吸困难、再次发热、X线胸片病变程度、淋巴细胞计数、动脉血气分析、C反应蛋白、心肌酶及部分生理学指标,差异有显著性;体温、发热天数、热型等差异无显著性。重症患者的多脏器衰竭、细菌感染、真菌感染的发生率高,使用抗病毒药、抗生素和糖皮质激素用量大、用药时间长,使用抗真菌药、呼吸机治疗的比例高于轻症患者。结论呼吸困难、再次发热、淋巴细胞计数、C反应蛋白、X线胸片病变严重等是重症患者的主要临床特征,重症患者应综合治疗。
Objective To investigate the clinical characteristics of pneumonia of influenza A H1N1.Methods The clinical data of 30 patients with pneumonia of influenza A H1N1 werestudied retrospectively.Results Among the 30 patients,14 males,16 females,aged 17 ～ 54 years old.23.3% were complicated by other chronic diseases,26.7% were pregnant and ly-ing-in women.The mortality is 13.4%.Difficulty breathing,second fever,X-ray chest radio-graphy,lymphocyte count,artery blood gas,C-reactive protein,myocardium enzyme,and some physiological index had significant difference in critical pneumonia of influenza A H1N1,compared with those mild cases.But body temperature,duration of fever and type of fever,hadno difference between the critical and the mild cases.Involvement of multiple organ,bacteria infection and fungus infection was open in the critical cases.Dosage and duration of antibiotics anti-viral drugs and corticosteriods in the critical cases were bigger and longer than the mild cases.Anti-fungus drugs and machine ventilation were used more frequently,compared with the mild cases.Conclusion Difficulty breathing,second fever,lymphocyte count,C-reactive protein,and X-ray chest radiography are the predominant clinical characteristics of the critical pneumonia of influenza A H1N1.The critical cases need general therapy.
出处
《哈尔滨医科大学学报》
CAS
北大核心
2011年第3期278-280,283,共4页
Journal of Harbin Medical University
关键词
甲型H1N1流感
肺炎
临床特点
influenza A H1N1
pneumonia
clinical characteristics
