摘要
目的探讨美沙拉嗪灌肠剂在溃疡性结肠炎(UC)治疗中的应用效果及其安全性。方法选取住院治疗的轻、中度UC患者41例,随机分为两组;治疗组给予美沙拉嗪灌肠剂(含美沙拉嗪4.0 g)每晚1次保留灌肠1周;对照组地塞米松5 mg加入生理盐水60 ml每晚1次保留灌肠1周。两组均给予地塞米松10 mg加入生理盐水100 m1静点3 d.同时口服美沙拉嗪1.0 g,每日3次,总疗程为2周。2周后观察疗效。结果两组患者治疗后症状及肠镜表现均明显改善(P<0.05)。两组治疗中均未发生严重不良反应。结论美沙拉嗪灌肠剂治疗UC疗效显著。
Obiective To observe the efficacy of rowasa enema on ulcerative colitis. Methods A total of 41 patients with ulcerative colitis were randomly divided into the control group （19 patients ） and the treatment group （22 patients ）. The control group was treated with dexamethasone sodium, the treatment group was given rowasa enema. The total period of treatment was 2 weeks. Results The total effective rate is 90.1% （ treatment group） vs 84.2% （ control group）. Conclusion Rowasa enema has curative effect on ulcerative colitis.
出处
《临床消化病杂志》
2011年第3期183-184,共2页
Chinese Journal of Clinical Gastroenterology
