摘要
目的探讨纤维支气管镜治疗慢性阻塞性肺疾病（chronic obstructive pulmonary disease，COPD）合并呼吸衰竭的临床疗效。方法将60例COPD合并呼吸衰竭的患者随机分为治疗组和对照组，每组30例；对照组常规抗感染、祛痰、吸氧等对症治疗。治疗组在此基础上通过纤维支气管镜吸痰、支气管肺泡灌洗；治疗2周后观察两组的临床疗效。结果治疗组中好转28例，有效率93．3％；对照组中好转21例，有效率70．0％，治疗组有效率高于对照组（P〈0．05）；临床症状、血气分析和肺功能改善明显，对照组比较差异有统计学意义（P〈0．01）。结论经纤维支气管镜治疗COPD合并呼吸衰竭患者疗效确切、安全，减轻症状，减少气管插管率，促进患者康复，具有重要的临床应用价值。
Objective To evaluate the efficacy of fiberbronchoscope in chronic obstructive pulmonary disease （COPD） patients with respiratory failure. Methods 30 patients with COPD were included in the study group after randomization, and 30 patients served as control group. The control group was treated by conventional anti-infective, expectorant, oxygen and other symptomatic treatment. The study group were added on the basis of suction and bronchoalveolar lavage through the bronchoscope. Clinical efficacy were observed after 2 weeks of treatment. Results Its improvement rate and clinical efficiency have been increased in study group than those of control group （ P 〈0.05）. Compared with the results of control group, study group improved significantly in clinical symptoms, blood gas indexes and pulmonary function （P 〈 0.01）. Conclusions The results suggest that fiberbronchoscope can offer confirmed efficiency and safety treatment in COPD patients with respiratory failure, and can alleviate symptoms,decrease endotraeheal intubation rate and promote recovery, with important clinical value.
出处
《国际呼吸杂志》
2011年第13期997-998,共2页
International Journal of Respiration
关键词
纤维支气管镜
慢性阻塞性肺疾病
呼吸衰竭
Fiberbronchoscope
Chronic obstructive pulmonary disease
Respiratory failure
