摘要
原发性高血压是遗传和环境因素共同作用的多基因复杂性疾病,新疆哈萨克族人群患病率高于同一居住区及不同居住区的其他民族,目前应用单核苷酸多态性(single nueleotide polymorphisms,SNPs)作为新一代遗传标志研究原发性高血压,对于阐明新疆地区哈萨克族人群的遗传易感机制具有重要意义。
Essential hypertension is a complicated polygene disease that involves genetic and environmental factors,which displays high prevalence among Kazakh people comparing with other people in the or different residential area.It is of great significance to elucidate the mechanisms underlying the genetic susceptibility in Xinjiang Kazakh population through the application of single nucleotide polymorphisms as a novel genetic marker for essential hypertension.
出处
《国际病理科学与临床杂志》
CAS
2011年第3期227-233,共7页
Journal of International Pathology and Clinical Medicine
基金
国家自然科学基金(30860079
30860102)~~
关键词
高血压
哈萨克族
候选基因
单核苷酸多态性
hypertension
Kazak
candidate gene
single nueleotide polymorphisms
