摘要
目的:了解细菌性腹泻患者的细菌菌群分布及耐药性特征,为预防治疗细菌性腹泻提供依据。方法:应用回顾性调查分析的方法,对我院2007～2010年739例细菌性腹泻患者粪便分离出的病原菌及细菌的耐药性进行分析。结果:分离鉴定出病原菌54株,总检出率为7.3%.病原菌以志贺菌36/54株(66.7%)居首位;鼠伤寒沙门氏菌9/54株(16.7%);念珠菌9/54株(16.7%)。各菌属对抗生素的敏感率不同,第四代头孢菌素较敏感,敏感率在90%以上。药物耐药性的大小依次为:青霉素类、氨基糖甙类、磺胺类、青霉素类复方制剂、喹诺酮类及头孢菌素类;碳烯青霉类未检出耐药菌。结论:志贺菌属是细菌性腹泻的首要病原菌。同时细菌性腹泻病原菌的耐药性在逐渐增加,应对腹泻患者进行耐药性监测,合理应用抗生素。
Objective：To analyze the microbes distribution and antibiotic resistance characteristic of the infectious diarrhea patients,and to supply guidance for prevention and cure.Methods： The character and resistance of the pathogenic bacteria,isolated from 739 cases of patients＇ stools during 2007 to 2010 in our hospital,were analyzed by retrospective study.Results：Fifty-four cases of pathogens were isolated and identified,the isolation rate was 7.3 %（54/739）.Shigella bacteria（36/54） 66.7% % was the first pathogenic bacteria.Salmonella typhimurium and nostoc occupied（9/54）16.7% respectively.Meanwhile,different bacteria has different sensitivity to antibiotics.The fourth generation cephalosporin was sensitive to more than 90% bacteria.The sequences of drug resistance from high to low were penicillin,aminoglycosides,sulfonamides,complex of penicillin,quinolones and cephalosporins.Conclusion：Shigella is the first pathogenic bacteria.According to the upgrade of the antibiotic resistance,it is necessary to monitor and reasonably apply the antibiotics.
出处
《西北国防医学杂志》
CAS
2011年第3期188-189,共2页
Medical Journal of National Defending Forces in Northwest China
关键词
细菌性腹泻
病原菌
耐药性
抗生素
Infectious diarrhea
Pathogens
Antibiotic resistance
Antibiotics
