摘要
目的分析子痫前期型肾病综合征的临床特点及其围产结局。方法回顾性调查2007年1月至12月在深圳市妇幼保健院住院的191例重度子痫前期患者,将43例重度子痫前期合并肾病综合征和148例重度子痫前期无合并肾病综合征患者分别作为病例组(肾病组)和对照组,分析两组临床资料,比较临床表现、生化指标和围产结局。结果肾病组多为年龄较轻的初产妇,病情重,以舒张压升高为主,低蛋白血症、肾功能受损、母婴并发症发生率显著高于对照组(均P<0.05)。结论子痫前期型肾病综合征病情重、进展快,对母婴的影响大,早期诊断、综合治疗和适时终止妊娠是提高围产质量的重要措施。
Objective To explore the clinical feature and pregnancy outcomes of pre-eclampsia with nephritic syndrome of pregnancy（NSP）.Methods 191 pregnant women with severe pre-eclampsia who were hospitalized in Shenzhen Maternity and Child Healthcare Hospital from January to December 2007 were retrospectively analyzed.The patients were divided into two groups according to pre-eclampsia with nephritic syndrome or without nephritic syndrome：case group included 43 cases,and control group included 148 cases.Blood pressure,biochemical indicators,maternal and fetal complications were compared between two groups.Results NSP was more likely to happen in younger primipara,with severely increased diastolic pressure,heavier proteinuria,lower plasma albumin level,renal insufficiency,more complication（P〈0.05）.Conclusion The perinatal prognosis of NSP is poor.Early diagnosis,comprehensive therapy and timely termination of pregnancy can improve the perinatal outcomes.
出处
《华中科技大学学报（医学版）》
CAS
CSCD
北大核心
2011年第3期340-342,共3页
Acta Medicinae Universitatis Scientiae et Technologiae Huazhong
关键词
子痫前期
肾病综合征
围产医学
pre-eclampsia
nephritic syndrome
perinatology
