摘要
探讨脑多肽治疗血管性痴呆的确切疗效。方法随机双育临床试验。第一疗程，观察组（A）63例，对照组（B）63例；第二疗程，采用交叉对照，AA组31例，AB组对例，BB组对倒，BA组32例，待疗效评定分析后揭盲。结果第一疗程疗效：总有效率观察组（A）为74．6％，对照组（B）为39．7％，两组经x2检验相差非常显著（P＜0．01）；第二疗程疗效：AA组总有效率为80．6％，经秩和检验两疗程间差异显著（P＜0．01）。经Ridit分析，以两疗程治疗组疗效最佳。副作用仅视察组尿素氮偏高。结论脑多肽治疗血管性痴呆近期疗效确切，副作用小，值得临床推广应用。
objective: To explore the method and effect of Nao-duotai in treating vascular dementia. Methods Randomised double-blind clinical trial was used for the first course of treatment. The cross control was used for the second course of treatment. Results The total response rate of treated group was 74. 6%,and that of the control group was 39. 7% in the first course of treatment. There was a great significance between the differences(P<0. 01). The total response rate of treated group was 80. 6%. There was remarkable significance between the two course differences being analysed by Rank sumtest (P<0.01). The two treated groups were better responded than other group with Ridit analyses. Adverse reaction was mild. Conclusion The effect of Nao-duotai in treating vascular dementia was significant.The adverse reaction was mild. It is worth selecting this drug for clinical use in vascular dementia.
出处
《中国综合临床》
1999年第5期410-411,共2页
Clinical Medicine of China
