摘要
目的医院获得性肺炎(HAP)居院内感染首位,特别是老年患者因免疫功能低下而易引发,严重影响老年人的生命健康。研究旨在探索有效防治老年医院获得性肺炎的治疗方案。方法通过观察100例老年医院获得性肺炎的患者,随机以单双号的方式分为试验组与对照组,两组均应用抗生素治疗,试验组在西药治疗基础上加用加减防风通圣散治疗。观察患者在入组后第3、7、10、14天C-反应蛋白与中性粒细胞计数等指标的变化情况。结果试验组第7天和第10天C-反应蛋白为(37.6±23.6)mg.L-1、(12.5±9.3)mg.L-1,而对照组第7天和第10天C-反应蛋白为(50.3±28.6)mg.L-1、(20.3±12.8)mg.L-1,试验组优于对照组,差异有统计学意义(P<0.01)。且试验组第7天和第10天中性粒细胞计数与对照组比较,差异亦有统计学意义(P<0.05)。结论加减防风通圣散联合西药治疗老年医院获得性肺炎效果明显优于单纯西药治疗方案,可减少病程,有利于患者康复,值得临床推广应用。
Objective The infection morbidity of hospital acquired pneumonia（HAP）is the highest in hospital.Specially,the elderly can be easily infected because of their lower immunity.The disease seriously affects the life and healthy state in the elderly.The study was aimed to explore the effective treatment program of senile HAP.Methods 100 cases of senile HAP were collected and randomized into a trial group and a control group.Antibiotics were applied in both groups.In trial group,on the basis of western medicine treatment,the modified fangfeng tongsheng powder was added.The changes in C-reactive protein（CRP）and neutrophil counts（NC）were observed on the 3rd,7th,10th and 14th days after the patients were included.Results CRP were（37.6±23.6）mg·L-1 and（12.5±9.3）mg·L-1 on the 7th and 10th days respectively in trial group and were（50.3±28.6）mg·L-1 and（20.3±12.8）mg·L-1 in control group respectively.The results in trial group were better than those in control group,presenting significant difference in statistics（P0.01）.The difference in NC on the 7th and 10th days was significant statistically in comparison between trial group and control group（P0.05）.Conclusion The combination program of the modified fangfeng tongsheng powder and western medicine is effective remarkably on senile HAP as compared with simple western medicine program.This integrated therapy can reduce the duration of treatment and benefit the rehabilitation of patients.Hence,it deserves to be promoted in clinical practice.
出处
《世界中西医结合杂志》
2011年第6期505-506,509,共3页
World Journal of Integrated Traditional and Western Medicine
关键词
防风通圣散
老年
医院获得性肺炎
临床观察
Fangfeng tongsheng powder
Senile
Hospital acquired pneumonia（HAP）
Clinical observation
