摘要
目的:探讨中医体质类型与慢性乙型重型肝炎(CSH)发病的关系。方法:临床收集浙江地区汉族慢性乙型重型肝炎(CSH,80例)、慢性乙型肝炎(CHB,60例)、慢性HBV携带者(ASC,40例)3组患者,后两组诊断均经肝活检证实。以王琦体质分类判定中医体质类型,比较组间体质类型分布的差异。结果:①CSH组与CHB组体质类型的分布未见统计学差异;②CSH组湿热质、阴虚质的分布频率(45.0%、25.0%)显著高于ASC组(7.5%、5.0%),平和质、气虚质、阳虚质的分布频率(6.2%、3.8%、2.5%)显著低于ASC组(42.5%、22.5%、15.0%),差异均有统计学意义(P<0.01)。结论:中医体质因素可影响慢性乙型重型肝炎的发生,湿热质和阴虚质慢性HBV携带者可能更易进展为CSH。
Objects： To investigate the association between TCM constitution type and chronic severe hepatitis B（CSH） in Chinese Han population.Methods： A total of 80 consecutive subjects with CSH and 100 patients with biopsy-proven hepatitis B virus infection（60 patients with chronic hepatitis B and 40 patients with asymptomatic HBV carrier） were studied.The constitution type was determined by Wangqi＇classification.Rerults： ①There was no significant differences about frequencies of constitution type between CSH group and chronic hepatitis B group.②The frequency of dampness-heat constitution and yin-deficiency in CSH group were significant higher（45%vs7.5%;25%vs5%）,the frequency of harmony constitution,qi-deficiency and yang-deficiency were significant lower（6.2%vs42.5%;3.8%vs22.5%;2.5%vs15%,respectively）,than those in asymptomatic HBV carrier group（P0.01）.Conclusion： TCM constitution type may play an important role in the development of CSH.Dampness-heat constitution and yin-deficiency constitution could facilitate the development of CSH in asymptomatic HBV carrier.
出处
《中华中医药杂志》
CAS
CSCD
北大核心
2011年第7期1492-1495,共4页
China Journal of Traditional Chinese Medicine and Pharmacy
基金
国家"十一五"科技重大专项(No.2008ZX10005-007
No.2009ZX10005-016)
浙江省中医药科技计划项目(No.2007CB199
No.2009WA010)~~
关键词
病毒性乙型肝炎
慢性重型肝炎
中医体质
Viral hepatitis B
Chronic severe hepatitis
TCM constitution type
