摘要
目的了解神经激肽Ｂ受体（ＮＫ３受体）与伤害性信息的传递和调制的可能关系，调查ＮＫ３受体在三叉神经尾侧亚核和脊髓内的分布状况。方法免疫组织化学技术。结果ＮＫ３受体样免疫反应产物在三叉神经尾侧亚核和脊髓内的分布基本一致。致密的免疫反应产物分布于Ⅱ内层（ｉｎｎｅｒｐａｒｔ），而Ⅰ层和Ⅱ外层（ｏｕｔｅｒｐａｒｔ）染色浅淡。ＮＫ３受体阳性神经元胞体主要见于三叉神经尾侧亚核和脊髓的Ⅰ层和Ⅱ层，少量分布于脊髓后角深层。
Objectives\ In order to study possible relationship between neurokinin B receptor(NK 3) and transmission and modulation of noxious sensory information, we investigated the distribution of NK 3 receptor in the caudal spinal trigeminal nucleus and spinal cord of the cat. Method\ Immunohistochemical staining was used. Results\ The distribution pattern of NK 3 receptor like immunoreactivity ( LI) in the spinal cord was similar to that of the caudal spinal trigeminal nucleus. Intense NK 3 receptor LI was observed in the inner part of lamina Ⅱ of the caudal spinal trigeminal nucleus and spinal cord; Weak NK 3 receptor LI was seen in lamina Ⅰ and outer part of lamina Ⅱ. Neuronal cell bodies with NK 3 receptor LI were mainly found in laminae Ⅰ and Ⅱ of the caudal spinal trigeminal nucleus and spinal dorsal horn, and a few were distributed in the deeper layers of the spinal dorsal horn. Conclusion\ The results suggest that NK 3 receptor might be involved in the transmission and modulation of primary noxious information in the caudal spinal trigeminal nucleus and spinal cord of the cat.
出处
《解剖学报》
CAS
CSCD
北大核心
1999年第3期197-198,I002,共3页
Acta Anatomica Sinica
基金
国家自然科学基金
关键词
神经激肽B受体
三叉神经
尾侧亚核
脊髓
猫
Neurokinin B receptor
Caudal spinal trigeminal nucleus
Spinal cord
Immunohistochemistry
Cat
