摘要
目的 :观察辅酶Q10 (CoQ10 )辅助性治疗充血性心力衰竭 (CHF)的疗效及分析其对预后的影响。方法 :对 161例CHF患者根据用药情况随机分为两组。Ⅰ组 72例 ,为基础抗心力衰竭治疗 ;Ⅱ组 89例 ,在基础抗心力衰竭治疗上加用CoQ10 ( 30～ 60mg/d) ,疗程为 8～ 12周。结果 :Ⅱ组与Ⅰ组相比 :总有效率提高显著 (P <0 0 1) ;心律失常、洋地黄中毒发生率明显降低 (P <0 0 5 ) ;病死率显著下降 (P <0 0 5 )。结论 :CHF患者在抗心力衰竭治疗基础上应常规使用CoQ10 ,这样既能提高疗效 。
OBJECTIVE:To detemine efficacy of coenzyme Q 10 treating congestive heart failure. METHOD:161 patients with congestive heart failure were divided into two groups receiving regular therapy and regular therapy plus CoQ 10 (30～60?mg/d;2～12 weeks).RESULTS:The effective rate in CoQ 10 ?group was significantly higher than that in regular group (P<0 01).The incidence of arrhythmia, digitalis poisoning and mortality rate decreased remarkably( P<0.05).CONCLUSION:The regular use of CoQ 10 ?is suggested for treating congestive heart failure to increase effective rate and lower mortality and incidence of complications .
出处
《九江医学》
1999年第3期137-138,共2页
Jiujiang Medical Journal
