摘要
目的：研究干扰素对流行性乙型脑炎病毒的抑制作用，为临床应用提供理论依据。方法：运用病毒滴定法，在培养病毒增殖系中投入干扰素（IFN），观察其对病毒增殖的影响。结果：用IEN300IU·ml-1处理后病毒产生量在人肝癌细胞HepG2和人神经母细胞瘤细胞株IMR-32中分别为对照的14％和1．6％。结论：IFN对乙脑病毒的增殖有显著阻碍作用。
TO study effective medicine fOr anti-epidemic encephalitis B virus serves as a theoretic evidence of clinicalpractice. METHODS:We observed antivity of interferon(IFN) on virus replication in the cultured cells with plaque forming. RE-SULTS: In the 300 IU.ml- 1 IFN,virus yields in human hepatorna cell line, HepG2 reduced to 14% of control level, virus growth inhuman neuroblastoma cell line IMR-32 was l. 6 % of control level. CONCLUSIONS: There results suggested that IFN markedly inhib-ited encephalitis B virus replication.
出处
《中国医院药学杂志》
CAS
CSCD
北大核心
1999年第9期519-520,共2页
Chinese Journal of Hospital Pharmacy
