摘要
通过动物实验观察不同程度活血化瘀药(和血药:当归、丹参;活血药:郁金、牛膝;破瘀药:莪术、虫)不同剂量(大剂量0.324g/100g、小剂量0.081g/100g)对大鼠CCl4轻度慢肝模型的治疗作用。结果显示:和血药当归、丹参大剂量组和活血药郁金、牛膝小剂量组能显著提高SOD活力,升高血清白蛋白含量,降低MDA、ALT。提示:活血化瘀药治疗慢肝损时,和血药剂量宜大,活血药剂量宜小,不宜选用破瘀药。
The curative effects of bloodquickening stasisdispelling medicinal with different degrees(Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae; Radix curcumae, Radix Achyranthis Bidentatae; Rhizoma curcumae, Eupolyphaga seu Steleophaga) and different dosages(large dosage: 0.324g/100g and small dosage:0.081g/100g) for mildly chronic hepatitis model(rat) induced by CCl4 were investigated through the animal experiment. As a result, the large dosage group of Radix Angelicae Sinensis and Radix Salviae Miltiorrhizae and small dosage group of Radix curcumae and Radix Achyranthis Bidentatae could greatly increase the SOD activity and serumalbumin level, and decrease MDA and ALT.
出处
《中成药》
CAS
CSCD
1999年第8期422-424,共3页
Chinese Traditional Patent Medicine
关键词
活血化瘀药
慢性
肝炎
中医药疗法
bloodquickening stasisdispelling medicinal, antichronic liver damage, ALT, hyperseralbumin, SOD, MDA