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不同方式终止14~24周妊娠的效果探讨 被引量:18

The effectiveness of different methods in termination of second trimester pregnancy
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摘要 目的:探讨不同方法终止14~24周妊娠的临床效果。方法:将117例妊娠14~24周妇女随机分为3组,A组采用米非司酮联合米索前列醇引产(40例);B组采用米非司酮联合羊膜腔内依沙吖啶注射引产(39例);C组采用羊膜腔内依沙吖啶注射引产(38例),比较3组引产效果。结果:A组与B组、C组相比,宫缩发动时间及产程短,清宫率低,镇痛药使用率低,出血量少,差异均有统计学意义(P〈0.05);B组与C组相比,宫缩发动时间及产程短,清宫率低,差异有均统计学意义(P〈0.05)。引产成功率3组间差异无统计学意义(P〉0.05)。结论:米非司酮联合米索前列醇引产简单、安全、高效,引产后不需常规清宫,优于米非司酮联合依沙吖啶引产和传统依沙吖啶引产,而米非司酮联合依沙吖啶引产优于传统依沙吖啶引产。 Objective: To investigate the clinical effectiveness of different methods in termination of second trimester pregnancy.Methods: A total of 117 women seeking for terminating 14-24 weeks of gestation in The Third Affiliated Hospital of South Medical University were randomly divided into three groups,group A(n=40,mifepristone combined with misoprostol),group B(n=39,mifepristone combined with amniotic cavity injection of rivanol) and group C(n=38,amniotic cavity injection of rivanol).The clinical effectiveness of these three methods was evaluated.Results: Compared with group B and C,shorter duration of labour induction,lower rate of post-abortion curettage,less use of analgesics and less amount of vaginal bleeding were found in group A(P all 0.05).Compared with group C,shorter duration of labor induction and lower rate of post-abortion curettage were observed in group B(P all 0.05).There were no significant differences in the clinical effectiveness among these three groups(P0.05).Conclusion: Mifepristone combined with misoprostol used for labour induction is superior to mifepristone combined with amniotic cavity injection of rivanol and traditional amniotic cavity injection of rivanol for its easy operation,safe,no need of curettage after induced abortion.In addition,mifepristone combined with amniotic cavity injection of rivanol for labour induction is superior to traditional amniotic cavity injection of rivanol.
出处 《中国计划生育学杂志》 北大核心 2011年第6期357-359,363,共4页 Chinese Journal of Family Planning
基金 广东省人口和计划生育委员会(2010334)
关键词 米非司酮 米索前列醇 依沙吖啶 引产 Mifepristone Misoprostol Rivanol Induced abortion
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